Peptide Purity Testing by LCMS

$200 per sample. 3–5 business day turnaround. Agilent LCMS with Diode Array Detection. Molecular weight confirmation, impurity identification, and a full Certificate of Analysis — mail-in from anywhere in the US.

🔬 Agilent LCMS-DAD Platform
📋 Full COA with Chromatogram
📦 Nationwide Mail-In Accepted
3–5 Business Day Results

Simple, Transparent Pricing

$200 / sample

Flat rate — no hidden fees

  • Purity percentage by LCMS-DAD
  • Molecular weight confirmation by MS
  • Impurity identification and quantification
  • Full chromatogram included in COA
  • 3–5 business day turnaround
  • COA accessible via public search portal
  • Analyst review and sign-off
Submit a Sample →

Add-On Tests

Content Analysis $25
pH Testing $30
Heavy Metals Screen $150
Endotoxin Testing $250
Sterility Testing $300

Rush processing available — contact us for availability and pricing.

What Your COA Includes

Every ZyntroTest peptide purity COA is generated from raw instrument data on our Agilent LCMS platform — not a template or estimate.

Purity Percentage

LCMS-DAD purity calculated from chromatogram peak areas. Reported as percentage of target compound versus total detected material.

Molecular Weight Confirmation

Mass spectrometric measurement of your peptide's molecular weight, confirming identity beyond retention time. Confirms the correct sequence is present.

Impurity Profile

Each detected impurity is identified (where structurally assignable) and quantified as a percentage. Deletion sequences, oxidation products, and synthesis by-products are reported individually.

Raw Chromatogram

The actual instrument output showing all peaks detected in your sample. The chromatogram is the verifiable evidence behind the purity number — included in every ZyntroTest COA.

Sample & Lot Information

Sample name, lot/batch number, receipt date, and ZyntroTest sample ID. Ties the COA to your specific submission — not a generic product certificate.

Analyst Sign-Off

Results reviewed and signed by a ZyntroTest analyst. Accessible via our public COA verification portal by sample ID — any buyer can confirm authenticity.

How to Submit Your Peptide Sample

1

Request Submission Form

Complete our online sample submission form with your compound name, expected purity, and any known sequences.

2

Package Your Sample

Ship minimum 5mg of sample in a sealed vial. Lyophilized or dissolved in DMSO both accepted. Label with your name and sample ID.

3

Ship to Our Lab

Mail to ZyntroTest, 1511 Texas Ave S, PMB 208, College Station, TX 77840. Standard shipping is fine — no dry ice required for most peptides.

4

We Run the Analysis

We confirm receipt by email, assign your sample to our queue, and run LCMS analysis on our Agilent platform within the standard 3–5 day window.

5

Receive Your COA

Your Certificate of Analysis is delivered by email and published to our public COA search portal. Pay securely upon receipt.

Start Your Submission →

Why LCMS — Not Just HPLC

Most peptide COAs in circulation are generated by HPLC with UV detection. Here's what that misses compared to LCMS.

Capability HPLC-UV (common) LCMS-DAD (ZyntroTest)
Purity measurement ✓ Yes ✓ Yes
Molecular identity confirmation ✗ No — retention time only ✓ Molecular weight by MS
Deletion sequence detection ✗ Often co-elutes, invisible ✓ Detected by mass difference
Oxidation product identification ✗ Hidden in main peak ✓ +16 Da resolved by MS
Novel impurity identification ✗ Cannot assign structure ✓ Mass spectrum reveals identity
Full UV spectral data ✗ Fixed wavelength only ✓ DAD: full spectrum across run
COA verifiability ✗ Purity number without ID proof ✓ Mass + UV + chromatogram

Read more: LCMS vs. HPLC — What Mass Spectrometry Shows That UV Detection Misses →

Peptide Purity Testing — Frequently Asked Questions

ZyntroTest charges $200 per sample for peptide purity testing. The price includes purity percentage by LCMS-DAD, molecular weight confirmation by mass spectrometry, impurity identification and quantification, a full chromatogram, and a Certificate of Analysis. No setup fees or hidden charges.
Standard turnaround is 3 to 5 business days from the date we receive your sample. Rush processing is available — contact us before shipping if you need results sooner than the standard window.
Every ZyntroTest peptide COA includes: purity percentage by LCMS-DAD, confirmed molecular weight by mass spectrometry, identification and quantification of detected impurities, the raw chromatogram, instrument method details, your sample information and lot number, and analyst sign-off. COAs are also published to our public COA search portal for buyer verification.
Yes. ZyntroTest accepts mail-in peptide samples from researchers, suppliers, and manufacturers anywhere in the United States. Ship to: 1511 Texas Ave S, PMB 208, College Station, TX 77840. See our sample submission page for packaging instructions.
HPLC-UV measures UV absorbance at a fixed wavelength — it can tell you how much of something is present but cannot confirm molecular identity. LCMS adds a mass spectrometer that measures molecular weight and fragmentation patterns, providing definitive identification in addition to quantification. For peptides, LCMS can detect deletion sequences, oxidation products, and amino acid substitutions that are invisible to HPLC-UV. See our detailed LCMS vs. HPLC comparison.
ZyntroTest is pursuing ISO/IEC 17025:2017 accreditation — the international standard for testing and calibration laboratories. The lab operates Agilent LCMS instruments following ISO 17025 quality system principles while formal accreditation is in progress.

Ready to Test Your Peptide?

$200 per sample · 3–5 business days · Full COA with chromatogram · Mail-in from any US state